• Deep Gupta
• Dr. Arti Kumari

The current study includes the blood metabolite and histopathological alterations induced by chronic (20 days) exposure of the fish Anabas testudineus to a sublethal concentrations (27.5 mg/L) of inorganic fertilizer, Urea [CO(NH2)2]. Significant changes were observed in the blood biochemical properties in the form of hyperglycemia, hyperproteinemia and hyperchlosterolemia. Some vital organs were taken for the histopathological study that is kidney, liver, intestine, testis and ovary. The present study showed major histopathological alteration like vacuolar degenerative changes, necrosis etc. found in liver, intestine, testis, ovary and kidney organs dysfunction in response to urea toxicity effect in the fish A. testudineus. So, it is suggested that more suitable to culture at water fertilizer, Urea concentration of < 27.5 mg/l for optimum growth performance. The information will be major role on different levels of responses of organisms with respect to pollutant stress is a necessary pre-requisite for the proper management of fertilizer application in agriculture and aquaculture.

Anabas testudineus, blood metabolite, fertilizer, histopathology, pollutant, Urea.

"UREA ENDUCED BLOOD METABOLIC & HISTOPATHOLOGY CHANGES IN VITAL ORGANS OF Anabas testudineus (Bloch.)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 4, page no.f187-f196, April-2022, Available :http://www.jetir.org/papers/JETIR2204526.pdf

"UREA ENDUCED BLOOD METABOLIC & HISTOPATHOLOGY CHANGES IN VITAL ORGANS OF Anabas testudineus (Bloch.)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 4, page no. ppf187-f196, April-2022, Available at : http://www.jetir.org/papers/JETIR2204526.pdf