• P.Shailaja
• A.Renuka
• B.Neerajakshi
• G.Snehalatha

The perfect delivery system will make the medicine soluble, transport the therapy to the desired location, and then release the therapy as needed to meet the specific needs of the patient and stage of the disease. One such efficient drug delivery system that overcomes the issues of drug toxicity and poor bioavailability is the use of nanosponges, which can carry both hydrophilic and hydrophobic medicines. Nanosponges have a nanometric cavity size, a 3-dimensional network, and are extremely small in size. Highly porous nanosponges have a special ability to entrap active molecules and have the advantage of programmable release. They are easy to make and safe for biological use. Different kinds of cyclodextrins can be cross-linked using a carbonyl or a dicarboxylate chemical as a cross-linker to create nanosponges. The use of nanosponge technology has been investigated for a number of purposes, including increasing the bioavailability of drug molecules and delivering medications via oral, topical, and parenteral routes. Enzymes, proteins, vaccines, and antibodies can all be delivered and released using nanosponges as a carrier for biocatalysts.

Nanosponges, cross-linkers, controlled release, cyclodextrins, bioavailability.

"NANOSPONGES: A PROMISING APROACH FOR DRUG DELIVERY SYSTEM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 9, page no.e882-e889, September-2022, Available :http://www.jetir.org/papers/JETIR2209505.pdf

"NANOSPONGES: A PROMISING APROACH FOR DRUG DELIVERY SYSTEM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 9, page no. ppe882-e889, September-2022, Available at : http://www.jetir.org/papers/JETIR2209505.pdf