• Ms.Gautami S.Kale
• Ms.Rohini B.Chougale
• Mr.Navneet N.Kharpe
• Ms.Arati A.Patil
• Mr.Satyajit Lad

Abstract : Natural polymers play a very important role in various pharmaceutical formulations. They are effortlessly accessible, low cost, biodegradable, non-poisonous, non-irritating and may be considered as pharmaceutical excipients. Nowadays investigation is ongoing for finding natural gums and mucilage for diversity of reasons including use in pharmaceutical formulations. The present study gives the information about Hibiscus rosa sinensis. Various plant gums had been used in the development of pharmaceutical formulations among them the gum obtained from the Hibiscus has its own identity in pharmaceutical and pharmacological world . Therefore, Diclofenac sodium tablets were formulated by employing Hibiscus rosa sinensis mucilage as a natural polymer to sustain the drug release from matrix system .The tablets were prepared by wet granulation process using different composition of mucilage with potato starch. The tablets were characterized for pre and post pressure parameters like, angle of response, tapped density, bulk density ,Carr's index , Hauser’s ratio ,friability and hardness, variation of weight, disintegration time, content uniformity and study of in-vitro drug release .The result shows the potential of Hibiscus rosa sinensis mucilage for use as binder for the preparation of uncoated tablet and for sustained release of drug formulation.

Hibiscus rosa sinensis ,Mucilage, Disintegration, Macerate

"Isolation And Characterization Of Mucilage From Hibiscus Rosa Sinensis As Tablet Binder And Release Modifier ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 12, page no.a34-a46, December-2022, Available :http://www.jetir.org/papers/JETIR2212006.pdf

"Isolation And Characterization Of Mucilage From Hibiscus Rosa Sinensis As Tablet Binder And Release Modifier ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 12, page no. ppa34-a46, December-2022, Available at : http://www.jetir.org/papers/JETIR2212006.pdf