• Asheesh Satpute
• Surendra dangi
• Dr.bhaskar Kumar Gupta

Liposome properties differ considerably with lipid composition, surface charge, size, and the method of preparation. Furthermore, the choice of bilayer components determines the ‘rigidity’ or ‘fluidity’ and the charge of the bilayer. For instance, unsaturated phosphatidylcholine species from natural sources (egg or soybean phosphatidylcholine) give much more permeable and less stable bilayers, whereas the saturated phospholipids with long acyl chains (for example, dipalmitoylphos phatidylcholine) form a rigid, rather impermeable bilayer structure. ). The liposomes prepared by physical dispersion method showed better percentage drug entrapment when compared with ether injection method. The particle size was analyzed by Malven particle size analyzer. The results of the particle size showed, when the concentration of soya lecithin was increased the size of the particle was reduced. The in vitro release showed that as the concentration of soya lecithin was increased the release rate of drug was retarded. Among the two methods ether injection method showed prolonged action when compared to physical dispersion method.

: Liposome,Phospholipid

"Formulation And Evaluation Of Flucinolone Acetonide Loaded Liposome Research Article of Asheesh ASHEESH Satpute", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 12, page no.a621-a627, December-2022, Available :http://www.jetir.org/papers/JETIR2212074.pdf

"Formulation And Evaluation Of Flucinolone Acetonide Loaded Liposome Research Article of Asheesh ASHEESH Satpute", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 12, page no. ppa621-a627, December-2022, Available at : http://www.jetir.org/papers/JETIR2212074.pdf