• JITHYA S MOHAN
• ARUN J.L

Nanogels are hydrogel nanoparticle consist of a network of cross-linked hydrophilic polymers.Nanogels are cross-linked polymeric nanoparticles that enlarge when exposed to particular solvent. Cross-linked networks comprising of a poly ion, a nonionic polymer (cross-linked polyethyleneimine ) and poly ethylene glycol are used for polynucleotide delivery . The remarkable expansion in the field of nanotechnology has prompted the need to develop Nanogel systems that have shown their potential to distribute medications in a continuous, regulated, and targetable manner.while clinical trials progress , it is practically impossible to avoid designing of sophisticated nano-systems that can be employed for therapy because of the rapidly expanding domain of polymeric sciences .This comprehensive study seeks to present exhaustive examples of novel Nanogel technologies, drug loading strategies, and drug release mechanisms. Moreover, a summary of the current state of Nanogels, the stage of clinical trials, and potential future applications has been included.

Nanogels, nanotechnology, nanoparticles, polymers, drug delivery system , drug release mechanism , stability.

"NANO GELS : AN INNOVATIVE CONCEPT FOR BOOSTING THERAPEUTIC PROFILE", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 12, page no.f225-f233, December-2022, Available :http://www.jetir.org/papers/JETIR2212532.pdf

"NANO GELS : AN INNOVATIVE CONCEPT FOR BOOSTING THERAPEUTIC PROFILE", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 12, page no. ppf225-f233, December-2022, Available at : http://www.jetir.org/papers/JETIR2212532.pdf