UGC Approved Journal no 63975(19)

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Published in:

Volume 10 Issue 8
August-2023
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2308354


Registration ID:
523342

Page Number

d433-d438

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Title

Synthesis, Characterization and Evaluation of Antibacterial Activity of 1-[(2-chloroquinolin-3-yl)methyl]pyridin-2(1H)one Derivatives

Abstract

Heterocyclic compounds are present in most of the drugs, having therapeutic activities such as anticancer, antiamoebic, antibacterial, antimalarial, anticancer, antiviral and anti-inflammatory etc. In biological and therapeutic activities, heterocyclic compounds play a crucial role in the core structures of many drugs. A usual example of bicyclic heterocyclic compounds is quinoline which is present as pharmacophore in number of drugs responsible for their therapeutic activity. 2-pyridone is also nitrogen containing six member heterocyclic compound acts as pharmacophore in number of drugs. In present work quinoline and 2-pyridone is coupled and synthesized compound is characterized by FT-IR, 1HNMR, spectral techniques and evaluated for its antibacterial activity against gram +ve Bacillus anthraces and gram -ve Pseudomonas aeruginosa bacteria. The coupled compounds showed moderate antibacterial activity against gram +ve bacteria (Bacillus anthraces) and gram –ve bacteria (Pseudomonas aeruginosa).

Key Words

Quinoline, 2-pyridone, Bacillus anthraces and Pseudomonas aeruginosa

Cite This Article

"Synthesis, Characterization and Evaluation of Antibacterial Activity of 1-[(2-chloroquinolin-3-yl)methyl]pyridin-2(1H)one Derivatives ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 8, page no.d433-d438, August-2023, Available :http://www.jetir.org/papers/JETIR2308354.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Synthesis, Characterization and Evaluation of Antibacterial Activity of 1-[(2-chloroquinolin-3-yl)methyl]pyridin-2(1H)one Derivatives ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 8, page no. ppd433-d438, August-2023, Available at : http://www.jetir.org/papers/JETIR2308354.pdf

Publication Details

Published Paper ID: JETIR2308354
Registration ID: 523342
Published In: Volume 10 | Issue 8 | Year August-2023
DOI (Digital Object Identifier):
Page No: d433-d438
Country: Karwi, Chitrakoot , Uttar Pradesh, India .
Area: Chemistry
ISSN Number: 2349-5162
Publisher: IJ Publication


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