• PRASHANT B. THORAT

Chirality has significant importance in chemistry and it is classified as sub-disciplines of chemistry. Many organic compounds which are found naturally such as, amino acids and vitamins are chiral. The concept of chirality was first introduced in 1815 by French chemist Jean Baptiste Biot when he discovered optical activity in nature. Since then, Chirality has become of tremendous importance in our daily life. Enantiomeric compounds have diverse chemical properties, these molecules have different tastes and odours. Hence, it is obvious that the two enantiomers of a molecule will interact differently with a living organism, as in some cases, only one enantiomer of a drug provides the desired effect while the other could be lethal. The broad utility of synthetic chiral molecules in pharmaceuticals, electronic and optical devices, as components in polymers with novel properties and as probes of biological function, has made to search for single enantiomer molecules. In this chapter focuses various asymmetric transformations using organic catalysts.

Organocatalysis, Asymmetric synthesis, L-proline derivatives, Applications, enantioselectivity

"Organocatalysis: An Asymmetric Approach", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 1, page no.b178-b195, January-2024, Available :http://www.jetir.org/papers/JETIR2401121.pdf

"Organocatalysis: An Asymmetric Approach", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 1, page no. ppb178-b195, January-2024, Available at : http://www.jetir.org/papers/JETIR2401121.pdf