• V. K. Dakhure
• M.K. Zate
• R. V. Sangvikar
• B. D. Gachande

In the present work, zinc oxide nanoparticles were successfully fabricated by using Momordica dioica Roxb. ex willd leaves aqueous extract as a reducing agent. The formed ZnONPs were characterised by UV-visible spectroscopy, X-ray diffraction (XRD), and SEM scanning electron microscopy. ZnONPs were confirmed by UV-visible spectra; the highest absorbance peak was found at 357 nm. The crystallite particle size was found in a range of 15.13 nm by XRD. Scanning Electron Microscopy (SEM) analysis confirms ZnONPs were granular-shaped and closely aggregated. In antioxidant activity, the IC-50 value of ZnONPs was found to be 669.46 μg/ml. Its antimicrobial activity was performed by the well diffusion method against Staphylococcus aureus and Escherichia coli. The highest antimicrobial activity of ZnONPs synthesised by Momordica dioica leaf extracts was found against Staphylococcus aureus (15 mm) and Escherichia coli (13 mm), respectively. The green synthesised ZnONPs have efficient antimicrobial activity against selected human pathogenic bacteria.

Nanoparticles, Antioxidant, Antimicrobial, M. dioica

"Characterization and Biological Applications of Zinc Oxide nanoparticles synthesized from M. dioica leaves extract ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 8, page no.f475-f482, August-2024, Available :http://www.jetir.org/papers/JETIR2408662.pdf

"Characterization and Biological Applications of Zinc Oxide nanoparticles synthesized from M. dioica leaves extract ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 8, page no. ppf475-f482, August-2024, Available at : http://www.jetir.org/papers/JETIR2408662.pdf