• Thaniyavarshini M
• Poornima SS
• Yogapriya P
• Mahibalan M
• Priyavarthini s

This research focuses on the development of Spirulina-integrated herbal bone cement for orthopedic and dental repair, aiming to create a sustainable, biocompatible, and infection-resistant alternative to conventional materials. Spirulina (Arthrospira platensis), rich in proteins, antioxidants, phycocyanin, and essential fatty acids, is combined with herbal extracts such as Tulsi (Ocimum tenuiflorum) or Neem (Azadirachta indica) to enhance the cement’s antimicrobial, antioxidant, and osteogenic properties. The formulation was prepared with Spirulina and Tulsi evaluated for mechanical strength, setting time, biodegradability, and antimicrobial activity. The results demonstrate that Spirulina-based bone cement not only supports bone regeneration and faster healing but also effectively prevents microbial infections, reducing reliance on antibiotic-loaded cements. This study highlights the potential of eco-friendly, herbal biomaterials as safer and more effective alternatives in orthopedic and dental applications, paving the way for advanced regenerative solutions.

Spirulina, Herbal bone cement, Tulsi extract, Neem extract, Orthopedic repair, Dental repair, Biocompatibility, Antimicrobial biomaterials, Sustainable implants.

"Spirulina Integrated Herbal Bone Cement for Orthopedic and Dental Repair ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.12, Issue 11, page no.e216-e222, November-2025, Available :http://www.jetir.org/papers/JETIR2511427.pdf

"Spirulina Integrated Herbal Bone Cement for Orthopedic and Dental Repair ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.12, Issue 11, page no. ppe216-e222, November-2025, Available at : http://www.jetir.org/papers/JETIR2511427.pdf