• Dr. Farha Luqman
• Dr. Mohd Zubair
• Dr. Mohd Tahir

Aloe barbadensis Miller (Aloe vera), a perennial succulent belonging to the family Asphodelaceae, is extensively recognised for its ethnomedicinal and pharmacological significance. Native to North Africa and now widely cultivated across tropical and subtropical regions, Aloe vera has been historically employed for wound healing, gastrointestinal disorders, and systemic rejuvenation. Its therapeutic values have historically served as a versatile remedy documented in classical texts such as De Materia Medica and Al-Qanun fi al-Tibb. Botanically, the plant is characterised by fleshy, triangular leaves that contain a clear, mucilaginous gel and a bitter, yellow latex, both of which are rich in bioactive compounds, including polysaccharides, anthraquinones, flavonoids, vitamins, enzymes, and minerals. Pharmacological studies have demonstrated its anti-inflammatory, analgesic, anti-arthritic, antioxidant, immunomodulatory, hepatoprotective, diuretic, laxative, and wound-healing activities. Classical Unani literature describes its actions as purgative, emmenagogue, carminative, and nerve-purifying, with applications across various conditions, including gastrointestinal, musculoskeletal, dermatological, and gynaecological disorders. Despite extensive traditional and contemporary research, notable gaps remain in standardisation, mechanistic elucidation, and clinical validation. Therefore, a comprehensive evaluation of Aloe vera’s ethnomedicinal, phytochemical, and pharmacological activities is essential. This review synthesises current evidence on aloe vera in oral health care, emphasizing its therapeutic relevance and potential for evidence-based applications.

Sibr, Aloe barbedensis, Unani medicine

"THE UNIVERSAL PANACEA: THERAPEUTIC AND PHARMACOLOGICAL INSIGHTS INTO SIBR (ALOE VERA)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.12, Issue 11, page no.f81-f94, November-2025, Available :http://www.jetir.org/papers/JETIR2511533.pdf

"THE UNIVERSAL PANACEA: THERAPEUTIC AND PHARMACOLOGICAL INSIGHTS INTO SIBR (ALOE VERA)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.12, Issue 11, page no. ppf81-f94, November-2025, Available at : http://www.jetir.org/papers/JETIR2511533.pdf