UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
Call for Paper
Volume 11 | Issue 3 | March 2024

JETIREXPLORE- Search Thousands of research papers



WhatsApp Contact
Click Here

Published in:

Volume 6 Issue 5
May-2019
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

7.95 impact factor calculated by Google scholar

Unique Identifier

Published Paper ID:
JETIRCN06018


Registration ID:
214931

Page Number

97-103

Share This Article


Jetir RMS

Title

A Novel Visible Spectrophotometric Validated Determination for the Assay of Doxycycline Hyclate in Pure and Pharmaceutical Samples

Abstract

A new introduced and sensitive method for the assay of Doxycycline hyclate has been proposed in pure and pharmaceutical samples. The current method is based on the reaction between Doxycycline hyclate and Ethylene diamine tetraacetic acid (EDTA) with ammonia which leads to the formation of a yellow colored complex having a λmax =444nm. The reaction conditions were optimized to obtain the complex of high sensitivity and longer stability. Under these optimum conditions, the absorbance of the complex were found to increase the linearly with increase in concentration of the drug, which was verified with correlation coefficient value .The system obeyed Beer’s law in the concentration range and Sandell’s sensitivity. The purpose of this review article is to present into the analyte in pharmaceutical preparations were in agreement with those of the obtained from a comparison method, as revealed by statistical analysis of the reported results using Student t-test and the variance F-test.

Key Words

Ammonia, Doxycyline, EDTA and spectrophotometry

Cite This Article

"A Novel Visible Spectrophotometric Validated Determination for the Assay of Doxycycline Hyclate in Pure and Pharmaceutical Samples", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 5, page no.97-103, May - 2019, Available :http://www.jetir.org/papers/JETIRCN06018.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"A Novel Visible Spectrophotometric Validated Determination for the Assay of Doxycycline Hyclate in Pure and Pharmaceutical Samples", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 5, page no. pp97-103, May - 2019, Available at : http://www.jetir.org/papers/JETIRCN06018.pdf

Publication Details

Published Paper ID: JETIRCN06018
Registration ID: 214931
Published In: Volume 6 | Issue 5 | Year May-2019
DOI (Digital Object Identifier):
Page No: 97-103
Country: Chennai, Tamil Nadu, India .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication


Preview This Article


Downlaod

Click here for Article Preview

Download PDF

Downloads

0002855

Print This Page

Current Call For Paper

Jetir RMS