• Rajesh K. Azad
• Harinder S. Banyal

Malaria is an infectious disease affecting millions of people around the globe. It is caused by intracellular protozoan parasite Plasmodium sp. Among the various biochemical strategies to combat the parasite, glutathione metabolism is of prime importance. The antioxidant enzyme such as Glutathione-S-Transferase (GST) protects cells from oxidative stress. During the present study GST activity was estimated electrophoretically in normal and parasitized fractions of blood of White Swiss Mice Mus musculus. The P.berghei infected blood showed broader achromatic zones than normal blood indicating higher GST activity than the normal blood. At the same time partial purification of GST was done using Ammonium Sulphate precipitation and Sephadex G-50.

Malaria, Glutathione, Glutathione-S-Transferase, Sephadex G-50

"Electrophoretic studies on Glutathione-S-Transferase and its partial purification from P.berghei infected rodent tissue", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 5, page no.396-399, May - 2019, Available :http://www.jetir.org/papers/JETIRCN06074.pdf

"Electrophoretic studies on Glutathione-S-Transferase and its partial purification from P.berghei infected rodent tissue", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 5, page no. pp396-399, May - 2019, Available at : http://www.jetir.org/papers/JETIRCN06074.pdf