• Priyeshnath Rathod

Nanotechnology has brought about a tremendous change in the field of medicine and pharmacy and still continues to do so. Nanosuspensions a form of this technology has proved its worth in the field of medicines. Drugs that were poorly soluble in aqueous as well as inorganic media were made available by use of nanosuspension technology. Transfer of materials into the nanodimension changes their physical properties which were used in pharmaceutics to develop a new innovative formulation principle for poorly soluble drugs: the drug nanocrystals. The drug nanocrystals do not belong to the future; the first products are already on the market. Nanosuspensions are prepared using various techniques like high pressure homogenization, media milling, solvent precipitation, etc. Lots of studies have been undertaken in developing method which is economical and can be expanded industrially. This is because drugs are usually expensive. There are advantages and disadvantages to all the methods available for preparing nanosuspensions. Usually high pressure homogenizer is preferred for preparing nanosuspensions as it can be industrially scaled up. Choice of polymeric surfactants for stabilizing nanosuspensions has been studied less. Storage stabilities of nanosuspensions have been determined using parameters like particle size and particle charge.

Nanotechnology has brought about a tremendous change in the field of medicine and pharmacy and still continues to do so. Nanosuspensions a form of this technology has proved its worth in the field of medicines. Drugs that were poorly soluble in aqueous as well as inorganic media were made available by use of nanosuspension technology. Transfer of materials into the nanodimension changes their physical properties which were used in pharmaceutics to develop a new innovative formulation principle for poorly soluble drugs: the drug nanocrystals. The drug nanocrystals do not belong to the future; the first products are already on the market. Nanosuspensions are prepared using various techniques like high pressure homogenization, media milling, solvent precipitation, etc. Lots of studies have been undertaken in developing method which is economical and can be expanded industrially. This is because drugs are usually expensive. There are advantages and disadvantages to all the methods available for preparing nanosuspensions. Usually high pressure homogenizer is preferred for preparing nanosuspensions as it can be industrially scaled up. Choice of polymeric surfactants for stabilizing nanosuspensions has been studied less. Storage stabilities of nanosuspensions have been determined using parameters like particle size and particle charge.

"Nanosuspension Approach for Drug Delivery System: A Review ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 5, page no.458-461, May 2019, Available :http://www.jetir.org/papers/JETIRCQ06087.pdf

"Nanosuspension Approach for Drug Delivery System: A Review ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 5, page no. pp458-461, May 2019, Available at : http://www.jetir.org/papers/JETIRCQ06087.pdf