• Kavita. M. Heda

Carbohydrates, “The building blocks of life” comprises the most abundant group of natural product. They are prime biological substances, which are metabolized as monosaccharides, oligo-saccharides and polysaccharides. They are indispensable for living organism, serving as skeletal structure in plants and also in insects. They also occur as food reserves in the storage organs of plants and in the liver and muscles of animals. In addition, they are an important source of energy required for the various metabolic source of energy required for the various metabolic activities of the living organism. The energy being derived as a result of their oxidation. They also serve to lubricate skeletal joint, to provide adhesion between cells and they confer biological specificity on the surface of animal cell. Series of new 1-Tetra-O-Benzoyl-β-D-Glocosyl-3-aryl (nitro substituted aniline)-2-phenyl thiocarbamide 2-S-benzyl-isothiocarbamide was prepared by the interaction of the of 1-Tetra-O-Benzoyl- β -D Glocosyl-3-aryl (nitro substituted aniline)-2-S-benzyl-isothiocarbamide and Phenyl thiocarbamide in benzene medium. The Reaction was refluxed for 3hr in benzene medium. After completion of the reaction, the reaction mixture was brought to room temperature and the solvent removed under reduced pressure to obtain residue. This residue was triturated several times with petroleum ether (60-80oC) to afford a pale yellow solid. Product was purified from chloroform-petroleum ether. The newly synthesized compounds have been characterized by analytical and IR, 1HNMR and Mass spectral studies. These compounds were screened for their antibacterial activities against–Escherichia coli, Staphylococcus aurous. These compounds show appreciable activity towards these microorganisms.

Phenyl Thiocarbamide, substituted s-Benzyl isothiocarbamide, Phenyl isothiocyanate, and Biological studies.

"Synthesis & screening for antimicrobial activity of N-Glucosylated aryl substituted s-benzyl isothiocarbamide", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 4, page no.41-44, April-2024, Available :http://www.jetir.org/papers/JETIRGF06011.pdf

"Synthesis & screening for antimicrobial activity of N-Glucosylated aryl substituted s-benzyl isothiocarbamide", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 4, page no. pp41-44, April-2024, Available at : http://www.jetir.org/papers/JETIRGF06011.pdf