ISSN: 2349-5162 | Impact Factor: 5.87

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Volume 4 Issue 3
eISSN: 2349-5162

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Effect Of Nicorandil On Serum Potassium Levels In Patients With Coronary Artery Disease.


Nicorandil is an antianginal drug, which has both nitrate-like and ATP-sensitive potassium (K-ATP) channel activator properties. Activation of potassium channels by nicorandil causes expulsion of potassium ions into the extracellular space leading to membrane hyperpolarization, closure of voltage-gated calcium channels and finally vasodilation. However, on the other hand, being an activator of K-ATP channel, it can expel potassium ions out of the cells and it can cause hyperkalemia. This review is to investigate the effect of nicorandil on serum potassium levels and to determine the beneficial effects of nicorandil in coronary artery disease patients.

Key Words

Nicorandil, Coronary artery disease, Potassium, Hyperkalemia.

Cite This Article

"Effect Of Nicorandil On Serum Potassium Levels In Patients With Coronary Artery Disease.", International Journal of Emerging Technologies and Innovative Research (, ISSN:2349-5162, Vol.4, Issue 3, page no.9-11, March-2017, Available :

Publication Details

Published Paper ID: JETIR1703004
Registration ID: 170110
Published In: Volume 4 | Issue 3 | Year March-2017
DOI (Digital Object Identifier):
Page No: 9-11
ISSN Number: 2349-5162

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Impact factor: 5.87

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