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Published in:

Volume 5 Issue 12
December-2018
eISSN: 2349-5162

Unique Identifier

JETIR1812B88

Page Number

706-711

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Title

Regioselective Synthesis and Structural Correlations of Aryl Pyrazole Framework

ISSN

2349-5162

Cite This Article

"Regioselective Synthesis and Structural Correlations of Aryl Pyrazole Framework", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 12, page no.706-711, December-2018, Available :http://www.jetir.org/papers/JETIR1812B88.pdf

Abstract

A regioselective synthesis of medicinally important methoxylated aryl pyrazole frameworks viz. 1-methyl-5-(2,4,6-trimethoxyphenyl)-1H-pyrazole 6 and 1-methyl-3-(2,4,6-trimethoxy-phenyl)-1H-pyrazole 7 were achieved by varying the addition sequence of methyl iodide and sodium hydride. The structures of the regioisomers were confirmed using 1D and 2D NMR techniques.

Key Words

Pyrazole, N-alkylation, Regioselectivity, HMBC

Cite This Article

"Regioselective Synthesis and Structural Correlations of Aryl Pyrazole Framework", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 12, page no. pp706-711, December-2018, Available at : http://www.jetir.org/papers/JETIR1812B88.pdf

Publication Details

Published Paper ID: JETIR1812B88
Registration ID: 194464
Published In: Volume 5 | Issue 12 | Year December-2018
DOI (Digital Object Identifier): http://doi.one/10.1729/Journal.19226
Page No: 706-711
ISSN Number: 2349-5162

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Cite This Article

"Regioselective Synthesis and Structural Correlations of Aryl Pyrazole Framework", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 12, page no. pp706-711, December-2018, Available at : http://www.jetir.org/papers/JETIR1812B88.pdf




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