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Published in:

Volume 5 Issue 12
December-2018
eISSN: 2349-5162

Unique Identifier

JETIR1812C67

Page Number

461-471

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Title

Study of Alterations in Enzymatic Antioxidants, Carbohydrate Metabolism and Pancreatic Histomorphology in Monocrotophos Exposed Balb/c mice

ISSN

2349-5162

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"Study of Alterations in Enzymatic Antioxidants, Carbohydrate Metabolism and Pancreatic Histomorphology in Monocrotophos Exposed Balb/c mice", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 12, page no.461-471, December-2018, Available :http://www.jetir.org/papers/JETIR1812C67.pdf

Abstract

The present study was undertaken to comprehend the lethal effects of organophosphorus insecticide Monocrotophos exposure on carbohydrate metabolism in Balb/c mice. Mice were procured, acclimatized and segregated in to 3 experimental groups, G-1 (control), G-2 (0.5 LD50) and G-3 (0.75 LD50). Mice were sampled on day 0, 7, 14 and 21 of the experiment. In G-3, blood glucose level was significantly (p<0.05) enhanced. Serum enzymes GOT, GPT, LDH were significantly (p<0.05) elevated in both Monocrotophos treated groups compared to control. Among treated groups, G-3 showed significantly (p<0.05) elevated blood and serum parameters compared to G-2. Serum amylase activity was found stable and no significant (p>0.05) alteration was observed in both treated and control groups. Present study concluded that the Monocrotophos has a significant (p<0.05) effect on carbohydrate metabolism and pancreatic histology.

Key Words

Monocrotophos, Carbohydrate metabolism, organophosphorus insecticide, pancreatic morphology.

Cite This Article

"Study of Alterations in Enzymatic Antioxidants, Carbohydrate Metabolism and Pancreatic Histomorphology in Monocrotophos Exposed Balb/c mice", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 12, page no. pp461-471, December-2018, Available at : http://www.jetir.org/papers/JETIR1812C67.pdf

Publication Details

Published Paper ID: JETIR1812C67
Registration ID: 221848
Published In: Volume 5 | Issue 12 | Year December-2018
DOI (Digital Object Identifier):
Page No: 461-471
ISSN Number: 2349-5162

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Cite This Article

"Study of Alterations in Enzymatic Antioxidants, Carbohydrate Metabolism and Pancreatic Histomorphology in Monocrotophos Exposed Balb/c mice", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 12, page no. pp461-471, December-2018, Available at : http://www.jetir.org/papers/JETIR1812C67.pdf




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