• DR. SANDEEP GARG

The present study was undertaken to comprehend the lethal effects of organophosphorus insecticide Monocrotophos exposure on carbohydrate metabolism in Balb/c mice. Mice were procured, acclimatized and segregated in to 3 experimental groups, G-1 (control), G-2 (0.5 LD50) and G-3 (0.75 LD50). Mice were sampled on day 0, 7, 14 and 21 of the experiment. In G-3, blood glucose level was significantly (p<0.05) enhanced. Serum enzymes GOT, GPT, LDH were significantly (p<0.05) elevated in both Monocrotophos treated groups compared to control. Among treated groups, G-3 showed significantly (p<0.05) elevated blood and serum parameters compared to G-2. Serum amylase activity was found stable and no significant (p>0.05) alteration was observed in both treated and control groups. Present study concluded that the Monocrotophos has a significant (p<0.05) effect on carbohydrate metabolism and pancreatic histology.

Monocrotophos, Carbohydrate metabolism, organophosphorus insecticide, pancreatic morphology.

"Study of Alterations in Enzymatic Antioxidants, Carbohydrate Metabolism and Pancreatic Histomorphology in Monocrotophos Exposed Balb/c mice", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 12, page no.461-471, December-2018, Available :http://www.jetir.org/papers/JETIR1812C67.pdf

"Study of Alterations in Enzymatic Antioxidants, Carbohydrate Metabolism and Pancreatic Histomorphology in Monocrotophos Exposed Balb/c mice", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 12, page no. pp461-471, December-2018, Available at : http://www.jetir.org/papers/JETIR1812C67.pdf