• S. Janet Beula
• Dr. R. Suthakaran
• Rajaram Das
• Laxmidar Sahoo
• Dr. J. Muthu Mohammed

ABSTRACT: Fluorescein is a manufactured organic compound and dye. It is available as a dark orange or red powder slightly soluble in water and alcohol. It is widely used as a fluorescent tracer for many applications. The IUPAC name of fluorescein is 3',6'-Dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one.It is prepared by heating phthalic anhydride and resorcinol over a zinc catalyst, and it crystallizes as a deep red powder. Now a days fluorescein and its derivatives are used as an Antioxidant, Antibiotics, Anti-inflammatory, Anti cancer, Anti fungal, detection of skin ulcers and detection of ophthalmic infections etc. The aim of this review is to provide the recent efforts of scinentists in applications of fluorescein, importants and synthesis of fluorescein derivatives, pharmacological action of fluorescein and their biological activity.

Fluorescein, Anticancer, Antibiotics, Insecticidal, Anti-inflammatory, Anti fungal.

"A REVIEW ON FLUORESCEIN, FLUORESCEIN DERIVATIVES AND THEIR APPLICATIONS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 5, page no.272-280, May-2019, Available :http://www.jetir.org/papers/JETIR1905045.pdf

"A REVIEW ON FLUORESCEIN, FLUORESCEIN DERIVATIVES AND THEIR APPLICATIONS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 5, page no. pp272-280, May-2019, Available at : http://www.jetir.org/papers/JETIR1905045.pdf