• Pooja Kolhe
• Dr P R Rajput

Literature survey reveals that 1,3 thiazine nucleus containing derivatives have a broad spectrum of biological as well as physiological activities.In the present segment of study some new chlorosubstituted 1,3 thiazines have been synthesized by condensation of 2 -hydroxy 3,5 dichloro 4 phenyl chalcone with thiourea and phenyl thiourea in ethanol containing aqueous KOH solution. The structures of newly synthesized chlorosubstituted thiazines have been elucidated on the basis of molecular weight determination, elemental analysis and spectral data. The newly synthesized chlorosubstituted 1,3 thiazines were prepared from chalcone and screened for their antifungal activity against Aspergillus niger,Candida albicans,Pencillium chrysogenum and Tricoderma viridae using agar diffusion method .

Chlorosubstituted 1, 3 thiazines, Chalcone, Antifungal activity

"Eco friendly synthesis, characterization and antifungal study of chlorosubstituted thiazines", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 5, page no.605-608, May-2019, Available :http://www.jetir.org/papers/JETIR1905189.pdf

"Eco friendly synthesis, characterization and antifungal study of chlorosubstituted thiazines", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 5, page no. pp605-608, May-2019, Available at : http://www.jetir.org/papers/JETIR1905189.pdf