• Dr.K.Sasikumar
• S.Benazir Hazira
• M.Sellappan
• S.Senthilnathan

Abstract Endocrine disrupting chemicals (EDCs) are known to disrupt normal metabolism and can influence the incidence of obesity in animals and humans. EDCs can exert adverse effects at low concentrations, often in a non-monotonic dose-related fashion. Among EDCs, Diethylene glycol dibenzoate (DGB), an approved alternative to phthalates in the production of plastic and latex products, however, is less abundant and its effects are almost completely unknown. The present study focused on the changes elicited Diethylene glycol dibenzoate (DGB) by on the enzyme activity Catalase and Superoxide dismutase of the various organs (muscle, gill, and liver) of Zebrafish. The observation registered in this study reflects that antioxidant enzymes activities were significantly enhanced in all the tissues (muscle, gill, and liver) when compared to control (untreated DGB). This could be due to the detoxification mechanism exhibited by the Zebrafish on exposure of DGP. The finding provides a support for the hypothesis that DGB may be the environmental contaminant with stress property.

Diethylene glycol dibenzoate, Zebrafish, Catalase, Superoxide dismutase, Antioxidant defense

"Antioxidant Enzymatic effects of Diethylene glycol dibenzoate(DGP) on Zebrafish (Danio rerio)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 5, page no.718-729, May-2019, Available :http://www.jetir.org/papers/JETIR1905999.pdf

"Antioxidant Enzymatic effects of Diethylene glycol dibenzoate(DGP) on Zebrafish (Danio rerio)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 5, page no. pp718-729, May-2019, Available at : http://www.jetir.org/papers/JETIR1905999.pdf