• Saniya Shaikh
• Prof. Razia Engineer

Contact lens wearers are at great risk of developing microbial keratitis and other ocular infections. These infections are often associated with inadequate lens hygiene (incorrect usage and unhygienic maintenance). Therefore, contact lens care products should be able to sufficiently minimize the amount of pathogens that are responsible for these infections. The present study was aimed at evaluating and comparing the disinfecting properties of three contact lens disinfecting solutions against potential bacterial and fungal pathogens. Three most widely used lens care solutions were tested according to the Stand Alone Test of ISO14729 [2001] against the standard strains of Staphylococcus aureus ATCC6538, Pseudomonas aeruginosa ATCC9027 and Candida albicans ATCC10231. In addition, effectiveness of multipurpose solution (MPSs) on conventional and silicon hydrogel lenses was investigated by biocide uptake studies. The three contact lenses disinfecting solutions passed the minimum disinfection criteria recommended by the ISO14729 Stand-Alone Test. Biocide uptake study showed considerable uptake of OptiFree Express solution by silicone hydrogel lenses resulting in reduction of biocidal efficacy of the solution. The present study also showed that the lens matrix significantly affect the disinfection efficacy of contact lens solutions by adsorbing the active biocide. This adsorbed biocide cause redness, corneal abrasions and inflammatory events in the eyes. Therefore, opticians should recommend a lens care solutions based on the composition and material of the lenses they prescribe to the lens wearer.

Contact lens care solutions, microbial keratitis, ISO14729, MPSs

"Study of biocidal efficacy of contact lens disinfecting solutions against common ocular pathogens ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 5, page no.611-620, May-2019, Available :http://www.jetir.org/papers/JETIR1905H97.pdf

"Study of biocidal efficacy of contact lens disinfecting solutions against common ocular pathogens ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 5, page no. pp611-620, May-2019, Available at : http://www.jetir.org/papers/JETIR1905H97.pdf