• NAGAMALLI ARASAVALLI
• Dr. DAISY RANI. ALLI

Volatile Organic Compounds (VOC) are a wide range of carbon based organic chemical compounds which evaporate easily at room temperature referred as volatile in nature. Human exhaled breathe consists of carbon dioxide (CO2) along with more than 3000 Volatile Organic Compounds exists like acetone, methanol, ethanol, and butane and formaldehydes etc. Out of existing several invasive methods, Exhaled breath analysis is a non-in vasive technique through which most preferable pain less procedures can be adopted for the purpose of diagnosing cancer cell/tissue detection. A MEMs based Bio-sensor design and fabrication using specific process flow methods is the main objective for detection of respiratory disease detection such as lung cancers. Many biomarkers are globally available among those only few suitable VOC gases are selected for the estimation and the level of severity or stages of Cancers. For this purpose, A MEMs VOC sensor structures must be designed using COMSOL software and suitable physics applied to achieve high sensitivity and accuracy, response time, repeatability of bio sensor. Based on the surface roughness obtained cancer cell topologies, malignancy can be predicted thereby reduce mortality.

VOC components, cell culturing, lung cancers, Bio-markers, MEMS.

"BIO MARKER BASED ESTIMATION OF CANCER CELL DETECTION BY HUMAN EXHALE VOC BREATH ANALYSIS USING MEMS SENSORS.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 5, page no.214-217, May-2019, Available :http://www.jetir.org/papers/JETIR1905K29.pdf

"BIO MARKER BASED ESTIMATION OF CANCER CELL DETECTION BY HUMAN EXHALE VOC BREATH ANALYSIS USING MEMS SENSORS.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 5, page no. pp214-217, May-2019, Available at : http://www.jetir.org/papers/JETIR1905K29.pdf