• ANKUR JOHARI
• VEER PAL
• MOHSIN HASAN KHAN

The extract of root and fruits of Calotropis gigantea which obtained by common methods were screened to check the activity against microbes and its phytochemical activities. The solvent used for their extraction were benzene, acetonic methanol, ethanolic and aqueous. The extract material was tested against skin diseases ,causing bacterial pathogens such as Staphylococcus aureus, Streptoccocus pyogenes and P. Aeruginosa using the well diffusion method. The aqueous, ethanolic and acetone extraction of root of C. gigantea inhibition against all the test microbe range between 7 mm to 13 mm diameter inhibitory zone. The same solvent extract of fruits of calotropis gigantea inhibition against all the test microbe ranging from 8 mm to 15 mm diameter inhibitory zone. The present study, bacterial extract showed a varying zone of inhibition of growth of tested organism than methenol, benzene, ethanol, and aqueous. Phytochemical properties of root and fruits of calotropis gigantea obtain from methanol, benzene, acetone, ethanol and aqueous extract were investigated.The obtained results indicate the presence of antibacterial activity and phytochemical in extract of calotropis gigantea against the human pathogenic bacteria.

Screened, Phytochemical activity, Calotropis gigantea, S. aureus, P.areogenosa, S.pyogenes.

"“ Extraction and Isolation ,Phytochemical analysis and Antimicrobial activity (against skin bacteria and some other bacteria ) of Calotropis gigantea in different organic solvent”", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 5, page no.3254-3261, May-2019, Available :http://www.jetir.org/papers/JETIR1905V46.pdf

"“ Extraction and Isolation ,Phytochemical analysis and Antimicrobial activity (against skin bacteria and some other bacteria ) of Calotropis gigantea in different organic solvent”", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 5, page no. pp3254-3261, May-2019, Available at : http://www.jetir.org/papers/JETIR1905V46.pdf