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Published in:

Volume 7 Issue 7
July-2020
eISSN: 2349-5162

Unique Identifier

JETIR2007003

Page Number

15-23

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Title

A Concise Audit on the Screening Models for the Pharmacological Evaluation of Type-II Anti-Diabetic Medications

ISSN

2349-5162

Cite This Article

"A Concise Audit on the Screening Models for the Pharmacological Evaluation of Type-II Anti-Diabetic Medications ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 7, page no.15-23, July-2020, Available :http://www.jetir.org/papers/JETIR2007003.pdf

Abstract

Background: The frequency of diabetes all over the globe has grown exotically over the recent past decades, and the vogue will continue for the anticipated future. The development of micro- and macro vascular complications is the dominant concern related to diabetes, whose contribution is highly proportional to the morbidity and mortality of the population with the disease. Advancement of the disease from pre-diabetic state to overt diabetes and the development of complexity transpire over many years. Reckoning of interventions crafted to delay or prevent disease amelioration or complexity in humans also takes years and desires impregnable resources. Objective: None the less, for an animal model to have more convenience to the study of diabetes, the features of the animal model should portray the patho-physiology and natural history of diabetes or the model should flourish the complications of diabetes with an etiology congruent to that of the human condition. Use of the suitable animal model based on these homogeneities can provide much needed data on patho-physiological mechanisms operative in human type 2 diabetes mellitus. Methods: A literature search was overseen by serving different keywords like "Type-II Diabetes Mellitus", " Anti-diabetic ", "In-vitro models" and "In-vivo models". The search was made to order by implementing convenient filters with a desire to fetch the best suited articles to meet the objective of this review article. Result: There are different research and review papers based on the anti-diabetic screening models for the determination of anti-diabetic activity of new drug molecules.

Key Words

Type 2 diabetes mellitus; animal models; rodents; Insulin; Glucose

Cite This Article

"A Concise Audit on the Screening Models for the Pharmacological Evaluation of Type-II Anti-Diabetic Medications ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 7, page no. pp15-23, July-2020, Available at : http://www.jetir.org/papers/JETIR2007003.pdf

Publication Details

Published Paper ID: JETIR2007003
Registration ID: 234896
Published In: Volume 7 | Issue 7 | Year July-2020
DOI (Digital Object Identifier):
Page No: 15-23
ISSN Number: 2349-5162

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Cite This Article

"A Concise Audit on the Screening Models for the Pharmacological Evaluation of Type-II Anti-Diabetic Medications ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 7, page no. pp15-23, July-2020, Available at : http://www.jetir.org/papers/JETIR2007003.pdf




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