• Nutrisia Latjindung

This research is expected to be able to assess the correlation between levels of High Sensitivity C-reactive protein (hs-CRP) and brain-derived neurotrophic factor (BDNF) in the urine of postmenopausal women who experience overactive bladder and do not experience overactive bladder at Adam Malik General Hospital Medan. An observational analytic reserach with case control design in menopausal paramedic women who experienced overactive bladder and did not experience overactive bladder at H Adam Malik General Hospital Medan in January 2019. The research sample was taken by non-probability method with consecutive sampling technique. If the data is normally distributed, the Pearson correlation test is used and if the data are not normally distributed, the Spearman correlation test is used. Hs-CRP level in OAB patients was >1,04 mg/L in 38 patients (100%), and in non OAB patient, hs-CRP level was < 1,04 mg/L in 37 patient (97,3%) with p value = 0,001. BDNF level in OAB patient was > 305,5 pg/L in 38 patients (100%) and in non OAB patient was > 305,5 pg/L in 38 patients (100%). Correlation between hs-CRP and BDNF in patients with OAB with r = 0.525 and p <0.001 while in patients without OAB, r = 0.128 and p = 0.442 (p <0.001). This research shows a significant correlation where hs-CRP levels rise, BDNF will also increase in OAB patients. but there is no correlation between hs-CRP and BDNF in patients without OAB.

High Sensitivity C-reactive protein (hs-CRP), brain-derived neurotrophic factor (BDNF), overactive bladder, menopause

"CORRELATION BETWEEN LEVELS OF HIGH SENSITIVITY C-REACTIVE PROTEIN (hs-CRP) AND BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF) IN THE URINE OF MENOPAUSAL WOMEN WHO EXPERIENCED OVERACTIVE BLADDER AND DID NOT EXPERIENCE OVERACTIVE BLADDER AT H.ADAM MALIK GENERAL HOSPITAL MEDAN", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 7, page no.537-541, July-2020, Available :http://www.jetir.org/papers/JETIR2007368.pdf

"CORRELATION BETWEEN LEVELS OF HIGH SENSITIVITY C-REACTIVE PROTEIN (hs-CRP) AND BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF) IN THE URINE OF MENOPAUSAL WOMEN WHO EXPERIENCED OVERACTIVE BLADDER AND DID NOT EXPERIENCE OVERACTIVE BLADDER AT H.ADAM MALIK GENERAL HOSPITAL MEDAN", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 7, page no. pp537-541, July-2020, Available at : http://www.jetir.org/papers/JETIR2007368.pdf