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"Structure Based Virtual Screening Of Indole Derivatives As Anti Nipah Viral Agents", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 1, page no.480-491, January-2021, Available :http://www.jetir.org/papers/JETIR2101064.pdf

• Dr. Sruthi.K
• Meher Unnisa
• Mysa Maneesha
• Prof. M. Sumakanth

Nipah virus (NiV), a newly emergent zoonotic paramyxovirus, has reported to cause several outbreaks in humans and is mainly associated with severe encephalitic diseases. Till these days, neither vaccines nor drugs with best possible accession against the virus are available. To identify novel inhibitors of NiV-G using structure based virtual screening of indole derivatives was performed using CHEMBL database and PyRx Software. The Screened molecules were subjected to structure based molecular docking studies using the crystal structure of the NiV-G to virtually screen for novel inhibitors of NiV-G and 4 potential compounds with highest potential ability to inhibit the NiV-G were found.

Nipah virus, indole derivatives, virtual screening, molecular docking.

"Structure Based Virtual Screening Of Indole Derivatives As Anti Nipah Viral Agents", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 1, page no. pp480-491, January-2021, Available at : http://www.jetir.org/papers/JETIR2101064.pdf