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Published in:

Volume 8 Issue 1
January-2021
eISSN: 2349-5162

Unique Identifier

JETIR2101064

Page Number

480-491

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Title

Structure Based Virtual Screening Of Indole Derivatives As Anti Nipah Viral Agents

ISSN

2349-5162

Cite This Article

"Structure Based Virtual Screening Of Indole Derivatives As Anti Nipah Viral Agents", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 1, page no.480-491, January-2021, Available :http://www.jetir.org/papers/JETIR2101064.pdf

Abstract

Nipah virus (NiV), a newly emergent zoonotic paramyxovirus, has reported to cause several outbreaks in humans and is mainly associated with severe encephalitic diseases. Till these days, neither vaccines nor drugs with best possible accession against the virus are available. To identify novel inhibitors of NiV-G using structure based virtual screening of indole derivatives was performed using CHEMBL database and PyRx Software. The Screened molecules were subjected to structure based molecular docking studies using the crystal structure of the NiV-G to virtually screen for novel inhibitors of NiV-G and 4 potential compounds with highest potential ability to inhibit the NiV-G were found.

Key Words

Nipah virus, indole derivatives, virtual screening, molecular docking.

Cite This Article

"Structure Based Virtual Screening Of Indole Derivatives As Anti Nipah Viral Agents", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 1, page no. pp480-491, January-2021, Available at : http://www.jetir.org/papers/JETIR2101064.pdf

Publication Details

Published Paper ID: JETIR2101064
Registration ID: 304886
Published In: Volume 8 | Issue 1 | Year January-2021
DOI (Digital Object Identifier):
Page No: 480-491
ISSN Number: 2349-5162

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Cite This Article

"Structure Based Virtual Screening Of Indole Derivatives As Anti Nipah Viral Agents", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 1, page no. pp480-491, January-2021, Available at : http://www.jetir.org/papers/JETIR2101064.pdf




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