• Usha Devi
• Pooja Kumari
• Tushar Gupta

ABSTRACT: Ocular inserts play important role in evolution of eye diseases therapy. They are sterile, thin multi-layered, drug containing solid/semi-solid devices placed into a cul-de-sac/conjunctival sac which are designed for ophthalmic application. It also includes polymeric support, which may or may not contains drug in it. They offer several advantages as increasing the contact time and thus improving the drug bioavailability. They are classified on the basis of their solubility (soluble, insoluble, and bio-erodible) inserts. From inserts the release of drug depends on their diffusion, osmosis, and bio-erosion of the drug. In this review, we discussed the introduction, classification, ocular insert devices, mechanism of drug release in the eye, absorption of the drug in the eye, formulation methods of ocular inserts, and evaluation parameter of ophthalmic inserts. This review is written to present a brief information about the ophthalmic insert.

Ophthalmic Inserts, Ocuserts, Lacrisertis.

"Ophthalmic Insert: A Controlled Drug Delivery System for Eye Diseases", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 1, page no.1120-1127, January-2021, Available :http://www.jetir.org/papers/JETIR2101141.pdf

"Ophthalmic Insert: A Controlled Drug Delivery System for Eye Diseases", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 1, page no. pp1120-1127, January-2021, Available at : http://www.jetir.org/papers/JETIR2101141.pdf