• Nagare Jayashri Chhabulal

Topical drug delivery can be defined as the application of a drug-containing formulation to the skin for the direct treatment of skin disorders or skin manifestations of systemic disease. For example, psoriasis to limit the pharmacological or other pathological effects of the drug on the skin surface or on the skin. The topical drug delivery system includes a variety of pharmaceutical dosage forms such as semi-solids, liquid preparations, sprays, and solid powders. The most widely used semi-solid preparations for topical drug delivery include gels, creams, and ointments. Antifungal therapy is one of the most effective mechanisms for eliminating fungal infections to improve quality of life. Systemic treatment is usually reserved for nail infections, extensive skin infections, or those that do not respond to topical treatment. Conventional topical formulations cannot maintain and control long-term drug delivery and therefore require longer treatment periods or must be supplemented with oral therapy. Fungal infections require regular application of conventional formulations for a longer period of time. Emulgel will facilitate long-term drug contact with the skin, and also has the ability to change the skin properties of the drug, thus improving the local treatment of skin infections. The strategy is to create a drug contained in Nanoemulgel that can control the release of the drug to the surface of the skin for 24 hours. Emulsion stability problems were also overcome by making a drug-containing Nanoemulgel, where almond oil (%) and homogenization rate (rpm) were considered as toxic factors. create. on 3 different levels.

Topical Preparation, Eberconazole Nitrate, Nanoemulgel, Ringworm.

"FORMULATION DEVELOPMENT AND EVALUATION OF TOPICAL NANOEMULGEL OF EBERCONAZOLE NITRATE", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 8, page no.e50-e71, August-2022, Available :http://www.jetir.org/papers/JETIR2208406.pdf

"FORMULATION DEVELOPMENT AND EVALUATION OF TOPICAL NANOEMULGEL OF EBERCONAZOLE NITRATE", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 8, page no. ppe50-e71, August-2022, Available at : http://www.jetir.org/papers/JETIR2208406.pdf