• ZEENATH BEGUM
• SK. SUSHMA TAJ
• ZAHERA MUSKAN
• K. JYOTHI
• Dr. J.V.C Sharma

Mucoadhesive microspheres are a type of carrier-linked novel drug delivery system with a drug core and a completely polymer-coated outside. Their diameter ranges from 1 to 1000 µm. The contact between mucin surface and synthetic or natural polymer is known as mucoadhesion. Mucoadhesive microspheres place a significant role in this particular drug delivery system because of their small size and other effective characteristics. Mucoadhesive microspheres have advantages such as effective absorption and enhanced bioavailability of the drugs due to a high surface to volume intimate contact with the mucus layer, controlled release, and increased residence time at the absorption site. These factors contribute to improved and better therapeutic performance of drugs. Mucoadhesive microspheres have been created for systemic or local effects in the oral, buccal, nasal, ophthalmic, rectal, and vaginal regions. It has a high safety profile and is the perfect targeting mechanism. This review article gives the information about mucoadhesive microsphere, theories of mucoadhesion, preparation methods, advantages, disadvantages and applications of mucoadhesive microspheres.

Microsphere, Mucoadhesive microsphere, Bioadhesion, Mucoadhesive polymer, Novel drug delivery system.

"A REVIEW ON MUCOADHESIVE MICROSPHERES AND ITS RECENT ADVANCES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 6, page no.j325-j334, June-2023, Available :http://www.jetir.org/papers/JETIR2306946.pdf

"A REVIEW ON MUCOADHESIVE MICROSPHERES AND ITS RECENT ADVANCES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 6, page no. ppj325-j334, June-2023, Available at : http://www.jetir.org/papers/JETIR2306946.pdf