• Yogita Yadav
• Madhukar Gangadhar Kasar
• Rakesh Vithalrao Patil

Novel N-amino benzylthiolates were synthesized via multicomponent reaction of malononitrile, isothiocyanates and benzyl halides under conventional and solvent-free conditions. Various electron-donating and -withdrawing substitutes within both isothiocyanates and benzyl halides were used to demonstrate the efficiency of new methodology. A broad spectrum of antibacterial and antifungal activities were observed especially within benzyl halides containing electron-withdrawing aryl substituents.

Multicomponent synthesis, Solvent-free condition, N-Amino benzylthiolate, Antibacterial activity, Antifungal property

"Antimicrobial and Antifungal Evaluation of Novel N-Amino Benzylthiolates with Solvent-Free Synthesis", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 6, page no.k610-k618, June-2023, Available :http://www.jetir.org/papers/JETIR2306A79.pdf

"Antimicrobial and Antifungal Evaluation of Novel N-Amino Benzylthiolates with Solvent-Free Synthesis", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 6, page no. ppk610-k618, June-2023, Available at : http://www.jetir.org/papers/JETIR2306A79.pdf