• R.Sabitha
• Gopal.V
• Shanmugam Achiraman
• subramanian Abinaya
• S.Akilandeswari

ABSTRACT This study aimed at investigating in vivo anti-hyperglycaemic activity of ethanolic extract of various crude drugs used in the ethanolic plant extract polyherbal formulation (EPEPF) were Wrightia tinctoria, Terminalia chebula, Plumbago zaylanica, Persea macarantha, Coscinium fenestratum, Phyllanthus emblica and Zingiber officinale in (EPEPF) induced diabetic mice. The anti-hyperglycaemic property was measured through oral administration of plant extract powder formulation that is polyherbal formulation at doses of 200 and 400mg/kg body weight and Knowledge measures of blood glucose levels every hour for up to 24 hours a glucometer was used to determine hyperglycaemic levels. The poly-herbal formulation showed a dose reliant on anti-diabetic activity in Streptozotocin-induced diabetic mice. The plant’s extract powder poly-herbal formulation was significantly hyperglycaemic levels it reduces the blood sugar level. The report proves to the poly herbal formulation reduces oxidative stress. Feature in this formulation developed for preclinical studies and will use in anti-diabetic drugs.

Keywords: Polyherbal formulation, Plants extract, antidiabetic, Diabetic, blood glucose.

"In-vivo Anti-diabetic activity of the Polyherbal Formulation ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 7, page no.i24-i30, July-2023, Available :http://www.jetir.org/papers/JETIR2307804.pdf

"In-vivo Anti-diabetic activity of the Polyherbal Formulation ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 7, page no. ppi24-i30, July-2023, Available at : http://www.jetir.org/papers/JETIR2307804.pdf