• Dr.O.S.S.Chandana
• J.Lalitha

A simple, accurate, precise stability indicating HPLC method is developed for the determination of assay of quinapril. The chromatographic separation was achieved on a inertsil column,C18(150 X 4.6 ID) 5µm, It has a mobile phase consisting of a mixture of 40 volumes of mixed phosphate buffer and 60 volumes of acetonitrile. The detection wavelength is 239 nm. The method was validated for analytical parameters such as specificity, accuracy, precision, robustness and ruggedness as per ICH guidelines. The proposed method was found to be simple, accurate, precise, and robust and stability indicating HPLC method. Hence this method can be used for routine analysis.

RP-HPLC, quinapril, method development, validation.

"ASSAY METHOD DEVELOPMENT AND VALIDATION OF QUINAPRIL USING HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC METHOD", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 8, page no.d752-d758, August-2023, Available :http://www.jetir.org/papers/JETIR2308393.pdf

"ASSAY METHOD DEVELOPMENT AND VALIDATION OF QUINAPRIL USING HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC METHOD", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 8, page no. ppd752-d758, August-2023, Available at : http://www.jetir.org/papers/JETIR2308393.pdf