• Ms. Hankare P.D.
• Ms. Bhuvad S.A.
• Mr. Karanjkar M.M.

Abstract : Novel drug delivery system is a novel approach to drug delivery that addresses the limitations of the traditional drug delivery systems. Our country has a vast knowledge base of ayurveda whose potential is only being realized in the recent years. The effectiveness of any herbal medication is dependent on the delivery of effective level of the therapeutically active compound. Severe limitation exists in their bioavailability when administered orally or topically. Phytosomes are recently introduced herbal formulations that are better absorbed and as a result produce better bioavailability and actions than the conventional phyto-molecules or botanical extracts. In the recent days, most of the prevailing diseases and nutritional disorders are treated with natural medicines. Several plant extracts and phytoconstituents, despite having excellent bioactivity in vitro demonstrate less or no in vivo actions due to their poor lipid solubility or improper molecular size or both, resulting in poor absorption and bioavailability. So, much work has been directed towards the development of new concept in herbal delivery system i.e.,“phytosomes”. The term ‘phyto’ means plant while ‘some’ means cell-like. Phytosomes are little cell-like structure. The present review highlights the method of Preparation, properties, advantages, characterization, applications of phytosomes and highlights key findings of recent research work conducted on phytosomes with our own viewpoints which can give the new directions and advancements to herbal dosage forms and the technical aspects of phyto-phospholipid formulations to face the future challenges .

Phytosomes, Phospholipid, Phosphatydilcholine, Bioavailability

"Phytosomal Drug Delivery System A Novel Approach To Enhance Bioavailability: A Review", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 10, page no.f485-f495, October-2023, Available :http://www.jetir.org/papers/JETIR2310459.pdf

"Phytosomal Drug Delivery System A Novel Approach To Enhance Bioavailability: A Review", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 10, page no. ppf485-f495, October-2023, Available at : http://www.jetir.org/papers/JETIR2310459.pdf