• MR. TEJAS M. YEOLE
• MS. PRANJAL N. SHIRSATH
• MRS. DIPALI B. JOSHI

This article focuses on the administration of medicinal agents through the mucosa. Because the mucosal membranes are generally porous, medication can be swiftly absorbed into the systemic circulation and avoided by avoiding first-pass digestion. This makes the mucoadhesive drug delivery method one of the more attractive and inventive drug delivery technological advancements. Mucoadhesive drug delivery systems extend the length of the dosage form's residency at the absorption site by interacting with mucin molecules and the mucus layer covering the mucosal epithelial surface. This medication delivery method's main benefit is that it prolongs the dosage form's residence time at the application site. The buccal cavity's plentiful blood supply and relatively high mucosal permeability make it the perfect site for both local and systemic drug delivery. This review has covered the anatomy and composition of the mucosal membrane, mucoadhesion mechanism, permeation enhancers, and different evaluation techniques, in addition to providing a quick summary of the various theories and delivery system compositions. Furthermore, a literature review of the buccal mucoadhesive drug delivery system and the factors influencing it have also been covered. Though it acts as a barrier to shield underlying tissue, the buccal mucosa is more permeable than other possible passageways like the skin. Nevertheless, mucoadhesive research is still in its infancy, and more development is required before the idea can be successfully used to control medication delivery. To gather literature scientific data and information on the subject, several online search engines and scientific publications were used

Mucoadhesion, Buccal drug delivery system, Mucoadhesive, Mucoadhesive gels, Buccal Route, Mucus membrane

"AN OVERVIEW ON MUCOADHESIVE GEL IN BUCCAL DRUG DELIVERY SYSTEM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 1, page no.e570-e578, January-2024, Available :http://www.jetir.org/papers/JETIR2401468.pdf

"AN OVERVIEW ON MUCOADHESIVE GEL IN BUCCAL DRUG DELIVERY SYSTEM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 1, page no. ppe570-e578, January-2024, Available at : http://www.jetir.org/papers/JETIR2401468.pdf