• Vijay Devra
• Mahima Sharma

The kinetics and mechanism of Ciprofloxacin [CIP] oxidation in HClO4 medium with sodium N- chloro-p-toluene sulfonamide or chloramine-T (CAT) was investigated at 303 K. The rate of reaction was followed by first-order kinetics on [CAT] and [CIP] and inversely proportional to [H+] concentration. Activation parameters were assessed and the reaction was examined at various temperatures. P-toluene sulfonamide addition slows down the rate of reaction. 7-amino fluoroquinolone and p-toluene sulfonamide were the oxidation products detected, and the reaction's stoichiometry was found to be 1: 2. A mechanism and rate law have been proposed to account for the observed results.

Ciprofloxacin, chloramine-T, kinetics, mechanism, Acidic Medium.

"OXIDATIVE DEGRADATION OF CIPROFLOXACIN BY CHLORAMINE-T IN ACIDIC MEDIUM – A KINETIC AND MECHANISTIC APPROACH", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 2, page no.e34-e44, February-2024, Available :http://www.jetir.org/papers/JETIR2402406.pdf

"OXIDATIVE DEGRADATION OF CIPROFLOXACIN BY CHLORAMINE-T IN ACIDIC MEDIUM – A KINETIC AND MECHANISTIC APPROACH", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 2, page no. ppe34-e44, February-2024, Available at : http://www.jetir.org/papers/JETIR2402406.pdf