• Ms. Pranjal N. Shirsath
• Mr. Tejas M. Yeole
• Mr. Rahul N. Patil
• Dr. Sachin N. Kapse

By applying a medication formulation to healthy, intact skin, a transdermal drug delivery device delivers pharmaceuticals systemically in a painless manner. Without building up any medication in the dermal layer, the medication first enters the body through the stratum corneum before moving on to the deeper dermis and epidermis. In order to avoid the nausea and vomiting that come with motion sickness, transdermal medication administration was initially employed in 1981. It promotes the healing of bodily injuries. Transdermal drug delivery involves applying a medicated adhesive patch to the skin in order to penetrate the epidermis and enter the bloodstream and administer a prescribed dosage of medication. It facilitates the healing of an injured bodily component. Using a transdermal patch allows for a controlled release of medication into the patient, which is advantageous over other delivery methods like oral, topical, intravenous, i.m., etc. Typically, this is accomplished by either a porous membrane covering a reservoir of medication or by body heat melting thin layers of medication embedded in the adhesive. The primary drawback of transdermal administration systems is that, because the skin acts as a very strong barrier, only small-molecule drugs may easily pass through the skin and be administered this way. This review article provides an overview of transdermal patches, outlining their types and preparation techniques. An effective transdermal medication delivery method was developed. The medication in TDDS readily permeates the skin and reaches the intended location. Transdermal drug delivery methods were created to circumvent the issues associated with oral medication delivery. Since 1981, these systems have been used as dependable and safe means of delivering medications.

transdermal drug delivery system, transdermal patches, mucosal layer, mucous, TDDS, transdermal

"Transdermal Drug Delivery System", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.11, Issue 2, page no.g97-g111, February-2024, Available :http://www.jetir.org/papers/JETIR2402614.pdf

"Transdermal Drug Delivery System", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.11, Issue 2, page no. ppg97-g111, February-2024, Available at : http://www.jetir.org/papers/JETIR2402614.pdf