• Harsha A. Padwal
• Nutan B.Kamble
• Vinod S. Narayane

A relatively smaller member of the carp family, the gold fish was one of the earliest fish to be domesticated, and is still one of the most commonly kept aquarium fish. Most of the farmers associated with ornamental fish farming in India practice captive culture of goldfish. Like all other members of carp family gold fish too have good life span and it is also a prolific breeder. Its potential to tolerate and survive over the extreme conditions of temperature, pH, salinity, etc., makes it an excellent laboratory model to carry out various research studies. It is also known for its efficiency for being a mosquito bio-control agent apart from being just an ornamental fish. The fish is regularly used as model to study fish behavior, teratogenesis and ecotoxicity, which includes pesticide as well heavy metal toxicity. Several heavy metals find their ways in natural water bodies and affect aquatic animals adversely. Lead, in particular is highly toxic and carcinogenic to all animals including many aquatic organisms, because of its high toxicity, non-biodegradability and tendencies to undergo bio-magnification. Lead accumulates in the body of fish either through water or food. In the present investigation, adult live specimens of goldfish, Carassius auratus were procured from local vendor each weighing approximately 20 grams. They were first acclimatized to the laboratory conditions and then exposed to analytical grade lead acetate solutions at the concentration ten times lower than the recorded LC50 value. The fish were exposed to lead acetate for three different durations. The control set was maintained separately. Tissues were obtained for histopathological studies as autopsy samples. Sections of the tissues were stained with conventional HE stain. Histopathological observations included hepatic lesions, cytoplasmic degeneration, necrosis, nuclear degeneration etc. Shortening of muscle bundles were also evident. Irregular diameters, degeneration and atrophy of renal tubules and oedema were noticed in renal tissue. The results indicated the effect of lead toxicity nearly on all the vital organs.

heavy metals, Carassius auratus, liver, kidney, muscle, histopathology.

"STUDY OF LEAD INDUCED HISTOPATHOLOGICAL ALTERATIONS IN CRUCIAN CARP (CARASSIUS AURATUS)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 5, page no.46-52, May-2019, Available :http://www.jetir.org/papers/JETIRCB06007.pdf

"STUDY OF LEAD INDUCED HISTOPATHOLOGICAL ALTERATIONS IN CRUCIAN CARP (CARASSIUS AURATUS)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 5, page no. pp46-52, May-2019, Available at : http://www.jetir.org/papers/JETIRCB06007.pdf