• Abilash Sasidharannair Chandrakumari
• Pammy Sinha

Neoplasms of thyroid are the commonest type of the endocrine neoplasms across the globe. Papillary thyroid carcinoma (PTC) constitutes about 80% of thyroid neoplasms. Morphological overlapping is quiet common between follicular patterned thyroid neoplasms. This study was a cross-sectional analysis carried out over a period of two years and Immunohistochemical staining was carried out on all 50 cases. Our study showed 96.67% of PTC group had diffuse and strong staining with HBME-1, and the staining was not observed in 86.67% of benign lesions. There is a significant difference between PTC group and benign group for the HBME‑1 staining. The loss of CD56 expression was observed in 83.33% of malignant lesions. In benign lesions, staining prevalence of HBME‑1, CK19, and CD56 was 13.33%, 20%, and 100% respectively.

"Assessment of CD56, HBME-1 and cytokeratin 19 expressions in papillary thyroid carcinoma and benign thyroid nodule ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 5, page no.406-412, May-2019, Available :http://www.jetir.org/papers/JETIRCJ06092.pdf

"Assessment of CD56, HBME-1 and cytokeratin 19 expressions in papillary thyroid carcinoma and benign thyroid nodule ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 5, page no. pp406-412, May-2019, Available at : http://www.jetir.org/papers/JETIRCJ06092.pdf