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Published in:

Volume 7 Issue 3
March-2020
eISSN: 2349-5162

Unique Identifier

JETIRDN06040

Page Number

180-182

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Title

SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF A MANNICH BASES, AND ITS Cu (II) COMPLEX.

ISSN

2349-5162

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"SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF A MANNICH BASES, AND ITS Cu (II) COMPLEX.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 3, page no.180-182, March-2020, Available :http://www.jetir.org/papers/JETIRDN06040.pdf

Authors

Abstract

The synthesis of Cu(II) complex derived from Mannich base N-[l-ethyl, 1-piperidino (4hydroxyphenyl)]semicarbazide(EPHPS)andN1[1-(4-hydroxyphenyl)-1-morpholinopropyl] semicarbazide (HPMPS) derived by the condensation of 4-hydroxy propiophenone, morpholine and semicarbazide. Its structure has been confirmed on the basis of analytical, magnetic and spectral studies. The Cu(II) complex exhibit square-planar geometry. The antibacterial activity of synthesized ligand (EPHPS) ,HPMPS) and its Cu(II) complex was studied by the usual cup-plate-agar-diffusion method against Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria. The qualitative and quantitative antimicrobial activity test results proved that the Cu(II) complex is very active than the free ligand. The increase in antibacterial activity is due to faster diffusion of metal complex as a whole through the cell membrane or due to the combined activity effect of the metal and ligand.

Key Words

Mannich-base, Copper (II) complex, Anti-bacterial activity..

Cite This Article

"SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF A MANNICH BASES, AND ITS Cu (II) COMPLEX.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 3, page no. pp180-182, March-2020, Available at : http://www.jetir.org/papers/JETIRDN06040.pdf

Publication Details

Published Paper ID: JETIRDN06040
Registration ID: 229501
Published In: Volume 7 | Issue 3 | Year March-2020
DOI (Digital Object Identifier):
Page No: 180-182
ISSN Number: 2349-5162

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Cite This Article

"SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF A MANNICH BASES, AND ITS Cu (II) COMPLEX.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 3, page no. pp180-182, March-2020, Available at : http://www.jetir.org/papers/JETIRDN06040.pdf




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