• Avula Srinivas

In a one pot procedure , a series of novel mannose thiazolidinone derivatives 4a-g and 5a-g was prepared by condensation of (3aS,4S,6S,6aS)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carbaldehyde 3 with mercapto acids and primary amines in presence of ZnCl2 under both micro wave irradiation and conventional heating conditions. Compound 3 prepared from Methyl di acetone D- Mannose with primary acetonide deprotection and with oxidative cleavage .Characterization of new compounds has been done by means of IR, NMR, MS and elemental analysis. The nematicidal and anti bacterial activity of the compounds has also been evaluated

D-Mannose, Thiazolidinones, Microwave assisted synthesis, antimicrobial and nematicidal activity

"Synthesis and Biological Evaluation of Mannose Thiazolidinones", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 9, page no.11-26, September-2018, Available :http://www.jetir.org/papers/JETIRE006003.pdf

"Synthesis and Biological Evaluation of Mannose Thiazolidinones", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 9, page no. pp11-26, September-2018, Available at : http://www.jetir.org/papers/JETIRE006003.pdf