• Vaishnavi Nagthane
• Raut L. S
• Sanjay Dalvi
• R. R. Rakh

The Bacillus spp survive in large number of different habitats. They are well known as producers of a wide array of antagonistic compounds of different structures, having between 5 to 8% of the total genome devoted to biosynthesis of secondary metabolites. Most important bioactive molecules from the genus Bacillus, are non-ribosomal synthesized peptides and lipopeptides, polyketide compounds, bacteriocins and siderophores. Lipopeptides from Bacillus have very complex mechanisms of biosynthesis catalysed by non-ribosomal peptide synthetases (NRPSs), large enzyme complexes with modular structure, with each module being in charge for the incorporation of particular amino acid. In general, these compounds have a broad spectrum of antagonistic activity against plant pathogenic bacteria, fungi, and viruses. Most important molecules from this group, circular lipopeptides from surfactin, iturin and fengycin families affect the target cells on the membrane level. Bacillus strains exhibit their biocontrol capacity predominantly through inhibitory activity on the growth of plant pathogens, as well as inducing systemic resistance in plants and competing for ecological niches with plant pathogens. Naturally present in the immediate vicinity of plant roots, B. subtilis is able to maintain stable contact with higher plants and promote their growth. In addition, due to its broad host range, its ability to form endospores and produce different biologically active compounds with a broad spectrum of activity, B. subtilis as well as other Bacillus spp. are potentially useful as biocontrol agents.

Bacillus, Biocontrol, Lipopeptides, and Plant pathogens

"Bacillus spp As an Biocontrol Agent for Plant Disease Management", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 4, page no.56-66, April-2023, Available :http://www.jetir.org/papers/JETIRFW06007.pdf

"Bacillus spp As an Biocontrol Agent for Plant Disease Management", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 4, page no. pp56-66, April-2023, Available at : http://www.jetir.org/papers/JETIRFW06007.pdf