UGC Approved Journal no 63975

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 2 Issue 5
May-2015
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR1701124


Registration ID:
221916

Page Number

537-541

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Title

NEW ANALYTICAL METHODS FOR THE ASSAY OF TRIMETAZIDINE DIHYDROCHLORIDE IN PURE AND PHARMACEUTICAL FORMULATIONS

Abstract

Two simple and sensitive Spectrophotometric methods (A and B) for the determination of Trimetazidine dihydrochloride in Bulk samples and pharmaceutical formulations are described. Method A is based on oxidative coupling reaction using 2,6 dichloro Quinine -4 – Chlorimde (DCQC). Which yield reddish coloured complex is measured at max 520 nm. And method B is based on the formation of the blue coloured species, which the drug is treated with folin-cioclteu (FC) reagent under alkaline conditions with an absorption maximum of max 770nm. The results obtained by the proposed methods were good agreement with the labelled amounts

Key Words

Trimetazidine, dihydrochloride, Dictloro quinine – 4 chloramide (DCQC), folin-cioclteu (FC) reagent

Cite This Article

"NEW ANALYTICAL METHODS FOR THE ASSAY OF TRIMETAZIDINE DIHYDROCHLORIDE IN PURE AND PHARMACEUTICAL FORMULATIONS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.2, Issue 5, page no.537-541, May-2015, Available :http://www.jetir.org/papers/JETIR1701124.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"NEW ANALYTICAL METHODS FOR THE ASSAY OF TRIMETAZIDINE DIHYDROCHLORIDE IN PURE AND PHARMACEUTICAL FORMULATIONS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.2, Issue 5, page no. pp537-541, May-2015, Available at : http://www.jetir.org/papers/JETIR1701124.pdf

Publication Details

Published Paper ID: JETIR1701124
Registration ID: 221916
Published In: Volume 2 | Issue 5 | Year May-2015
DOI (Digital Object Identifier):
Page No: 537-541
Country: Visakhapatnam, Andhra Pradesh, India .
Area: Chemistry
ISSN Number: 2349-5162
Publisher: IJ Publication


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