UGC Approved Journal no 63975

ISSN: 2349-5162 | ESTD Year : 2014
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Volume 2 Issue 2
February-2015
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR1701453


Registration ID:
304158

Page Number

335-338

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Title

Influence of Melatonin and L – thyroxine to thymic cellular structure in a seasonally breeding rodent Funambulus pennanti

Abstract

The pineal gland and its principal neurohormone melatonin have been explored as a gland of physiological importance. However, another significant thyroid gland has proved its importance. Looking such view, we have focused our study on immunologically important thymic gland’s cellularity in a seasonally breeding rodent Funambulus pennanti. Pinealectomized squirrel revealed no clear-cut demarcation between thymic cortex and medulla region. Severe depletion of thymocytes in cortical region were observed. Melatonin treatment to the pinealectomize squirrels showed restoration of the thymic cellular structure. However, surgical of thyroid gland caused depletion of thymocytes in thymic lobules when compared to the sham control squirrels. L-thyroxine to the thyroidectomized squirrels showed almost same cellular architecture to that of sham control squirrels. Moreover, melatonin treatment along with L-thyroxine showed dense population of thymocytes in the cortex region. Study suggest synergistic action of both hormones on thymic cellularity.

Key Words

Melatonin, L- Thyroxine, thymocytes, synergistic action, thymic cellularity

Cite This Article

"Influence of Melatonin and L – thyroxine to thymic cellular structure in a seasonally breeding rodent Funambulus pennanti", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.2, Issue 2, page no.335-338, February-2015, Available :http://www.jetir.org/papers/JETIR1701453.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Influence of Melatonin and L – thyroxine to thymic cellular structure in a seasonally breeding rodent Funambulus pennanti", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.2, Issue 2, page no. pp335-338, February-2015, Available at : http://www.jetir.org/papers/JETIR1701453.pdf

Publication Details

Published Paper ID: JETIR1701453
Registration ID: 304158
Published In: Volume 2 | Issue 2 | Year February-2015
DOI (Digital Object Identifier):
Page No: 335-338
Country: -, -, - .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication


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