• Nitish Bhardwaj

Hydroxamic acid was reported by H. Lossen in 1869 due to the reaction of hydroxylamine on diethyl oxalate. The production of violet colouration with Fe (III) and green colouration with Cu (II) are the characteristic reactions of hydroxamic acids. Hydroxamic acids are generally prepared by the reaction of hydroxylamine on organic esters or its derivatives in presence of sodium ethoxide. Hydroxamic acid behaves as a bidentate chelating agent having complexing sites both of hydroxyl and carbonyl oxygen in which former loses a proton on forming a chelate. The structure of the hydroxamic acids was first brought to the attention of W. Lossen by the observation that the product obtained by the interaction of anisohydroxamic acid and benzoyl chloride was different from the product obtained with benzohydroxamic acid and anisoyl chloride. He introduced the term ‘metamers’ to describe these compounds erroneously believing that both acyl groups in each compound were attached to the nitrogen atom of the hydroxyl amine molecule.

anisoyl chloride, benzoyl chloride, metamers.

"HYDROXAMIC ACID : AN ANALYTICAL REAGENT FOR NUMBER OF ELEMENTS ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.4, Issue 1, page no.1089-1096, January-2017, Available :http://www.jetir.org/papers/JETIR1701569.pdf

"HYDROXAMIC ACID : AN ANALYTICAL REAGENT FOR NUMBER OF ELEMENTS ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.4, Issue 1, page no. pp1089-1096, January-2017, Available at : http://www.jetir.org/papers/JETIR1701569.pdf