• Suhail Rashid Mir

Both edible and ethnomedical plants, as well as all mammals and marine species, contain triterpenoids in large quantities. These substances have a variety of structural types and are distinguished by a 30 C backbone that has been altered in several ways that permits the creation of over 20,000 members. In plants, Acetate/mevalonate is the process that produces triterpenoids, and it is carried out in the endoplasmic reticulum and cytoplasm sections of the cell. With a wide range of pharmacological activities, including anti-inflammatory, anti-oxidant, antibacterial, antiviral,hepatoprotective, gastroprotective, cardioprotective, hypolipidemic, antiatherosclerotic, immunoregulatory, anticancer, and cancer prevention properties, triterpenoids have emerged as a significant class of secondary metabolites in recent years. According to various findings, triterpenoids block a variety of intracellular signaling molecules and transcription factors. The regulation of tumor cell proliferation, transformation, survival, invasion, angiogenesis, metastasis, chemoresistance, and radioresistance is also influenced by these chemicals. Advances in the synthesis of physiologically active triterpenoids are crucial because, despite these significant characteristics and the amaizing action mechanisms, medication development derived from triterpenoids is still hindered by the low yield from herbal extraction. This chapter gives an update on the anticancer properties of triterpenoids, their health benefits, and the state of triterpenoids synthetic production.

immunoregulatory, angiogenesis, metastasis

"General review of diversity of triterpenoids, and their pharmacological activities with special reference to cancer.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.3, Issue 1, page no.64-68, January-2016, Available :http://www.jetir.org/papers/JETIR1701C59.pdf

"General review of diversity of triterpenoids, and their pharmacological activities with special reference to cancer.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.3, Issue 1, page no. pp64-68, January-2016, Available at : http://www.jetir.org/papers/JETIR1701C59.pdf