UGC Approved Journal no 63975(19)

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Published in:

Volume 4 Issue 5
May-2017
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR1705081


Registration ID:
301754

Page Number

448-452

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Title

Comparative Analysis of Arsenic Levels in the Blood of Arsenic Induced Female Mice and Its Correlation with Ovarian Cancer Patients

Abstract

Arsenic is noxious metalloid that subsist everywhere in the surrounding and disturb worldwide health issue due to its carcinogenicity. Progressive increase of arsenic-related diseases and various types of cancer incidences were reported for the last few years in Bihar. Our work has focused on the toxic effects of arsenic exposure in the blood of mice and women. Female Swiss albino mice were selected as the experimental animals. In the treatment group 1.8 mg/kg body weight sodium arsenite and in control group distilled water was given orally by gavage method daily for 1 month, 2 months, 3 months, 4 months and 5 months. After the treatment of mice, blood samples were collected. Normal women and arsenic exposed ovarian cancer patients from arsenic affected districts of Bihar were selected as human model and blood samples were collected with their prior consent of the subjects. The levels of sodium arsenite of blood of all arsenic treated mice groups were significantly (p < 0.05 for Group A and for rest of the Groups, p < 0.01) higher than that of the control mice group. The arsenic levels were significantly (p < 0.05 for Bhagalpur district and for rest all districts p < 0.01) higher in ovarian cancer patients from all sample districts as compared to the normal group of women. Thus, the present work reveals the toxic effect of arsenic exposure in the blood of Swiss albino mice and women of arsenic hit districts of Bihar.

Key Words

Sodium Arsenite, Swiss Albino Mice, Blood, Ovarian Cancer Patients.

Cite This Article

"Comparative Analysis of Arsenic Levels in the Blood of Arsenic Induced Female Mice and Its Correlation with Ovarian Cancer Patients", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.4, Issue 5, page no.448-452, May-2017, Available :http://www.jetir.org/papers/JETIR1705081.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Comparative Analysis of Arsenic Levels in the Blood of Arsenic Induced Female Mice and Its Correlation with Ovarian Cancer Patients", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.4, Issue 5, page no. pp448-452, May-2017, Available at : http://www.jetir.org/papers/JETIR1705081.pdf

Publication Details

Published Paper ID: JETIR1705081
Registration ID: 301754
Published In: Volume 4 | Issue 5 | Year May-2017
DOI (Digital Object Identifier):
Page No: 448-452
Country: bhopal, MP, India .
Area: Biological Science
ISSN Number: 2349-5162
Publisher: IJ Publication


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