UGC Approved Journal no 63975

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 4 Issue 6
June-2017
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR1706098


Registration ID:
303831

Page Number

523-525

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Title

Ultrastructural alteration in liver of diabetic mice and repaired by aqueous leaf extract of Carica papaya

Abstract

A significant role of Carica papaya aqueous leaf extract was observed in the liver of hyperglycemic swiss albino mice under surface electron microscopic examination. Diabetic mice treated with aqueous leaf extract of Carica papaya for 56 days at one time dose of 150 mg/kg body weight for orally daily. The total dose of Alloxan monohydrate (450 mg kgˉ¹ bwˉ¹) was administrated in three injections at interval of 48 hrs (150 mg kgˉ¹ bwˉ¹) each time. Mice with blood glucose level of greater than 200 mg/dl were considered diabetic and were selected for study. Remarkable changes that occurred in the liver of diabetic mice verses control mice. These changes include degenerative alteration represented by disorganization of the hepatic cords, vacuolated hepatocytes, cytoplasmic vacuolization and picnotic nuclei of hepatocytes and inflammatory cell infiltration.

Key Words

Hyperglycemic, Alloxan monohydrate, Carica papaya leaf, Aqueous extract, Scanning electron microscope

Cite This Article

"Ultrastructural alteration in liver of diabetic mice and repaired by aqueous leaf extract of Carica papaya ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.4, Issue 6, page no.523-525, June-2017, Available :http://www.jetir.org/papers/JETIR1706098.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Ultrastructural alteration in liver of diabetic mice and repaired by aqueous leaf extract of Carica papaya ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.4, Issue 6, page no. pp523-525, June-2017, Available at : http://www.jetir.org/papers/JETIR1706098.pdf

Publication Details

Published Paper ID: JETIR1706098
Registration ID: 303831
Published In: Volume 4 | Issue 6 | Year June-2017
DOI (Digital Object Identifier):
Page No: 523-525
Country: -, -, - .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication


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