• Shaishab Kumar Dinda

A green one pot synthesis of 6H-chromeno[4,3-b] quinolin-6-one derivatives which are the main core of the natural product of Polyneomarline C using ammonium thiocyanate is described. Reaction of 4-chloro-3-formyl coumarin or different β-chloro α-β-unsaturated aldehyde and different aromatic amine or 4-amino and 6-amino coumarin in water-methanol solvent (2:1) at 60 oC afforded the desired products. The advantages of this strategy are good yields, no chromatographic separation and free from oxidant, heavy metal catalyst and toxic by-products. The 4-chloro-3-formyl coumarin is obtained by Vilsmeier Haack reaction of 4-hydroxy coumarin.

6H-Chromeno[4,3-b] quinolin-6-one, green synthesis, ammonium thiocyanate, 4-chloro-3-formyl coumarin, neat reaction, Polyalthianemoralis C.

"A Green Approach for the Synthesis of 6H-chromeno[4,3-b] quinolin-6-one derivatives", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 4, page no.1401-1405, April-2018, Available :http://www.jetir.org/papers/JETIR1804449.pdf

"A Green Approach for the Synthesis of 6H-chromeno[4,3-b] quinolin-6-one derivatives", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 4, page no. pp1401-1405, April-2018, Available at : http://www.jetir.org/papers/JETIR1804449.pdf