UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 5 Issue 4
April-2018
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR1804449


Registration ID:
502003

Page Number

1401-1405

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Title

A Green Approach for the Synthesis of 6H-chromeno[4,3-b] quinolin-6-one derivatives

Abstract

A green one pot synthesis of 6H-chromeno[4,3-b] quinolin-6-one derivatives which are the main core of the natural product of Polyneomarline C using ammonium thiocyanate is described. Reaction of 4-chloro-3-formyl coumarin or different β-chloro α-β-unsaturated aldehyde and different aromatic amine or 4-amino and 6-amino coumarin in water-methanol solvent (2:1) at 60 oC afforded the desired products. The advantages of this strategy are good yields, no chromatographic separation and free from oxidant, heavy metal catalyst and toxic by-products. The 4-chloro-3-formyl coumarin is obtained by Vilsmeier Haack reaction of 4-hydroxy coumarin.

Key Words

6H-Chromeno[4,3-b] quinolin-6-one, green synthesis, ammonium thiocyanate, 4-chloro-3-formyl coumarin, neat reaction, Polyalthianemoralis C.

Cite This Article

"A Green Approach for the Synthesis of 6H-chromeno[4,3-b] quinolin-6-one derivatives", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 4, page no.1401-1405, April-2018, Available :http://www.jetir.org/papers/JETIR1804449.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"A Green Approach for the Synthesis of 6H-chromeno[4,3-b] quinolin-6-one derivatives", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 4, page no. pp1401-1405, April-2018, Available at : http://www.jetir.org/papers/JETIR1804449.pdf

Publication Details

Published Paper ID: JETIR1804449
Registration ID: 502003
Published In: Volume 5 | Issue 4 | Year April-2018
DOI (Digital Object Identifier): http://doi.one/10.1729/Journal.31446
Page No: 1401-1405
Country: -, -, India .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication


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