UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 5 Issue 5
May-2018
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR1805958


Registration ID:
314941

Page Number

1331-1342

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Title

Alternatives to Antibiotics: Current Trends and Future Perspectives

Abstract

The serendipitous discovery of antibiotics in the 20th century resulted in a major decline in infection related death rate, but soon after, overexploitation of antibiotics led to the development of antibiotic resistance in microbial populations. The emergence of multidrug resistance and extreme drug resistance in pathogens further intensified the whole situation. Around 100000-2000000 tons of antibiotics are being used in agriculture, horticulture, and medicine annually at a global level. The death rate due to antibiotic-resistant bacteria has risen far greater than the death rate due to HIV/AIDS and Tuberculosis. Modification of the site of action, efflux of antibiotics and degradation of drugs are the main mechanisms bacteria use as a defense strategy against antibiotics. Finding better drugs and methods to combat antibiotic resistance has become a need of the hour. This increase in antibiotic resistance has forced researchers to go back to the pre-antibiotic era in order to develop alternative drugs and processes to combat drug resistance. This review emphasizes the urgency of tackling this situation and deploy all promising alternatives of antibiotics like phage therapy, use of bacteriocins, organic acids, nanotechnology and CRISPR-Cas technique to address the antibiotic resistance challenge.

Key Words

Antibiotic, Drugs Resistance, Phage Therapy, Bacteriocins, Nanotechnology.

Cite This Article

"Alternatives to Antibiotics: Current Trends and Future Perspectives", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 5, page no.1331-1342, May-2018, Available :http://www.jetir.org/papers/JETIR1805958.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Alternatives to Antibiotics: Current Trends and Future Perspectives", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 5, page no. pp1331-1342, May-2018, Available at : http://www.jetir.org/papers/JETIR1805958.pdf

Publication Details

Published Paper ID: JETIR1805958
Registration ID: 314941
Published In: Volume 5 | Issue 5 | Year May-2018
DOI (Digital Object Identifier): http://doi.one/10.1729/Journal.28101
Page No: 1331-1342
Country: -, -, India .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication


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