• ANKITA TIWARI
• PALLAVI TIWARI
• MAYANK SRIVASTAVA
• SAURAV GHOSHAL

Abstract: Aim of The Study: Bambusa vulgaris Schrad. Ex J. C Wendl. (Poaceae), a rhizomatous plant commonly known as Golden Bamboo, is widely distributed and grows in tropical and sub tropical areas. It is cultivated extensively in many parts of the world especially in wild fields and wet tropics. Bamboo leave have been reported to be used as Astringent, Ophthalmic solution and febrifuge. Ethane botanically, Bambusa vulgaris is use in traditional medicine for the treatment of several disease (e.g. measles), as an abortifacient, an appetizer and for managing respiratory diseases. The leaves have also been used in India for treatment of various inflammatory conditions. The present research was aimed to evaluate the potential antiulcer activity of aqueous extracts of leaves in vivo models to validate to folkloric use of the plant. Materials and Method: The antiulcer activity of aqueous extracts of leave were studied on Female albino wistar rat, stomach damage induced by Indomethacin (20mg/kg) all the chemical, solvent and reagent used were of AR grade and were purchased from Tunnex chemicals, at the herbarium of Botany Department, University. The antiulcer activity of aqueous extracts of leaves were stuthe collected plant was identified and authenticated by the Botanical Survey in India, the collected leaves of Bambusa vulgaris were dried in shade at room temperature and reduced to course powder using a mechanical grinder. The dried powder material was extracted with Petroleum ether (60-8 0C) by Hot continuous extraction in a Soxhlet,s s apparatus for 48 h. The extract was concentrated under reduced pressure and stored in an air tight container. Histopathological change in stomach were also studies along with Ranitidine (20mg/kg) as standard antiulcer agent were determine to assess the effect of the aqueous extract of leave of Bambusa vulgaris (100, 150 and 200mg /kg) on the Indomethacin induced peptic damage . Result: The phytochemical investigation of the extract showed presence of carbohydrates, steroids and flavonoids. Pre- treatment of the rat with aqueous extract prior to Indomethacin administration, all the extracts showed the decrease in gastric juice. Volume on comparison to control group and indicated their anti-secretary effort. But 90% Aqueous extract (200mg/kg) showed significant effect on that of ranitidine (20mg/kg) in reducing the gastric juice volume. Compared the controlled group all the test extract showed elevation in pH indicating their capacity to reduce the acidity of the gastric juice, the 90% Aqueous extract At 200mg/kg indicate almost equipotent effect on that of Ranitidine. Gastric free acidity is increased in control animal due to ulcer. Conclusion: The result indicates that this plant possesses potential antiulcer properties and has therapeutic potential for the treatment of stomach diseases.

Bambusa vulgaris, Indomethacin, Antiulcer Activity, Ranitidine.

"ANTIULCER ACTIVITY OF ETHANOL EXTRACT OF LEAVES OF “BAMBUSA VULGARIS” (BAMBOO) AGAINST INDOMETHACIN – INDUCED PEPTIC ULCER IN RAT", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 6, page no.63-70, June-2018, Available :http://www.jetir.org/papers/JETIR1806130.pdf

"ANTIULCER ACTIVITY OF ETHANOL EXTRACT OF LEAVES OF “BAMBUSA VULGARIS” (BAMBOO) AGAINST INDOMETHACIN – INDUCED PEPTIC ULCER IN RAT", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 6, page no. pp63-70, June-2018, Available at : http://www.jetir.org/papers/JETIR1806130.pdf